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Characterization of plastic deformation in polycrystalline grains requires the investigation of such phenomena as crystallographic slip and twinning. A commonly used method to study these processes is the method based on the comparison of modelled crystal lattice strains with the values measured by diffraction. However, the use of model assumptions can cause some ambiguities regarding the values of the critical resolved shear stresses (CRSS) for the slip and twin systems and their evolution during plastic deformation. A diffraction method based on neutron diffraction measurements developed in this work, allows for direct measurement of stresses at selected groups of crystallites and then determination of resolved shear stresses (RSS) for slip and twin systems as well as their critical values (CRSS), without the use of deformation models [1,2]. The so obtained CRSSs were used as the input data for modified EPSC (Elastic-Plastic Self-Consistent) model and additionally the hardening parameters were estimated. Then, the same set of parameters describing twinning and crystallographic slips was used for the EPSC model to simulate four different modes of deformation. The model results were verified by comparison with experimental data (e.g. grain stress, RSS and texture). Acknowledgement: This work was financed by a grant from the National Science Centre, Poland (NCN), No. UMO-2023/49/B/ST11/00774.