Near-beta-titanium alloys present a compelling substitute for traditional medium-strength steels to achieve weight-reduction goals, supporting greener aviation and Net-zero targets. Near-beta-titanium alloys provide excellent corrosion resistance, high-temperature stability, low-thermal expansion, resilience, and durability. Use of these alloys, whilst promising, faces the challenge of sporadic failure stemming from insufficient local fracture toughness. This susceptibility is believed to be intricately tied to the microstructure, processing defects, and in-service loading conditions [1,2]. There exists a notable gap in research, particularly in robust microstructure-based materials modelling and prediction, leaving the phase or feature responsible for these sporadic failures largely unexplored. This work will focus on understanding the sporadic failure in metastable-beta-titanium alloys, viz. Ti5553, using microstructure-based modelling techniques developed in-house. Influence of alpha grains in the dual phase alloy are investigated via CPFEM to bring new insights into the deformation and possible failure mechanisms. REFERENCES (maximum 2 references) [1] Umair Bin Asim, Amir Siddiq, Mehmet E. Kartal, Representative Volume Element (RVE) based Crystal Plasticity study of Void Growth on Phase Boundary in Titanium alloys, Computational Materials Science, 161, 346-350, 2019. 2 P. Christie, M. A. Siddiq, R. M. McMeeking, M. E. Kartal, Interaction of defects, martensitic transformation and slip in metastable body centred cubic crystals of Ti-10V-2Fe-3Al: A study via crystal plasticity finite element methods (CPFEM), International Journal of Damage Mechanics, 34(1):157-185, 2025.